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Photodynamic therapy for the treatment of Barrett’s esophagus : a systematic review and economic evaluation

Description

Barrett's esophagus is a benign condition, usually caused by long-term gastroesophageal reflux disease. In some individuals the abnormal Barrett's tissue develops precancerous cells. Barrett's... More ≫

Description

Barrett's esophagus is a benign condition, usually caused by long-term gastroesophageal reflux disease. In some individuals the abnormal Barrett's tissue develops precancerous cells. Barrett's esophagus with high grade dysplasia is associated with a higher risk of developing one type of esophageal cancer. Interventions to remove the dysplastic tissue are intended to reduce this risk. Photodynamic therapy is one of several less invasive, endoscopic treatment options for Barrett’s esophagus that offer an alternative to surgical removal of the esophagus. This review assesses the evidence on the safety and effectiveness of photodynamic therapy for the treatment of Barrett's esophagus with high grade dysplasia in comparison to esophagectomy and other endoscopic treatments for this condition. It also examines the social and economic considerations for the provision of PDT in comparison to alternate treatments.

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Provincial flood damage assessment study

Description

This study updated/developed flood damage curves in select communities at risk of flooding to 2014 economic values and established adjustment indices for their use in different flood prone... More ≫

Description

This study updated/developed flood damage curves in select communities at risk of flooding to 2014 economic values and established adjustment indices for their use in different flood prone communities across Alberta. It also developed a computerized model for estimating flood damages and undertook flood damage estimates for select communities throughout Alberta.

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